Jerry Garcia of Grateful Dead

Jerome John "Jerry" Garcia (August 1, 1942 – August 9, 1995) was an American musician, songwriter, and artist best known for being the lead guitarist and vocalist of the psychedelic rock band the Grateful Dead. Garcia was viewed by the media as the leader or "spokesman" of the group.
Performing with the Grateful Dead for its entire three decade career (which spanned from 1965 to 1995), Garcia participated in a variety of side projects, including Legion of Mary, and the Jerry Garcia Band, Old and in the Way, the Garcia/Grisman acoustic duo, and several solo albums. Read more here.

Janis Joplin, The Queen of Blues

Janis Lyn Joplin (January 19, 1943 – October 4, 1970) was an influential singer, songwriter, and music arranger. She rose to fame in the 1960's as the lead singer of Big Brother and the Holding Company and eventually a solo career before her death from a drug overdose. She was one of the most popular and influential singers of the sixties and is considered to be one of the greatest female rockers of all time. In 2004, Rolling Stone magazine ranked Joplin #46 on their list of the 50 Greatest Artists of All TimeJanis Joplin was born to Seth Ward Joplin and Dorothy Bonita East. Her father was an engineer at Texaco. Her mother was the registrar at a business college. Janis had two younger siblings, Michael and Laura. As a teenager, she befriended a group of outcasts, including Jim Langdon and Grant Lyons, the latter of whom played her the blues for the first time. She began singing in the local choir and listening to musicians such as Leadbelly, Bessie Smith, Odetta, and Big Mama Thornton. While at Thomas Jefferson High School, she was mostly shunned. Among her high school classmates was another individual destined for stardom: future college and NFL coach Jimmy Johnson. In a 1992 Sports Illustrated profile of his career, Johnson claimed that he gave Janis the high school nickname of "beat weeds." Primarily a painter, in high school she first began singing blues and folk music with friends. More reading is here.